Uhlalutyo kuba uthelekiso ka-mtDNA ka-DNA Diagnostics Iziko yindlela ebalulekileyo kwi-instrument isigqibo nokuba umntu sele a biological budlelwane kwi-macala zabo oomama. Kubalulekile eyodwa kwi-njalo ugqatso kwi-maternity, apho ibhekiswe kwibhunga njalo ugqatso kwi-i maternity haplogroup ye-descent kuwe isiseko kwindlela yakho DNA kuphela. Igama elithi mtDNA liba lifutshane ukuba mitochondrial DNA, uhlobo DNA oko kukuthi ebone kwi-mitochondria, okanye yenza amandla"powerhouse", iiseli I-Mitochondrial DNA ngu ophunyezwe a umama wakhe nabantwana, ukuba kunjalo elide njengoko ngumsebenzi omkhulu inzuzo kwi-pagsinag kugqatso kwi-maternity ka-oyedwa(Xa bobabini oonyana neentombi ilifa mtDNA ezonweni zabo, umama wakhe, iintombi nje falling emfutshane yabo mtDNA abantwana babo.) Kwi mtDNA uhlalutyo ngokobuhlanga kwi-maternity, mtDNA ye-tested umntu ufumana wabeka kwi ukulandelelana (olukhankanywe ukulandelelana i-DNA molecules zabo mtDNA.) I-ukulandelelana ngu kuthelekiswa inokwenza ukuba umntu ufumana identical kugqatso kwi-maternity. I-ukulandelelana ye-mtDNA ka-abantu kunye afanelekileyo maternal, iya kubonisa similarities.
